| EC |
2.1.1.142 |
| Accepted name: |
cycloartenol 24-C-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + cycloartenol = S-adenosyl-L-homocysteine + cyclolaudenol |
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For diagram of sterol sidechain modification, click here |
| Glossary: |
cyclolaudenol = (24S)-24-methylcycloart-25-en-3β-ol |
| Other name(s): |
sterol C-methyltransferase |
| Systematic name: |
S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase |
| Comments: |
S-Adenosyl-L-methionine methylates the Si face of the 24(25)-double bond with elimination of a hydrogen atom from the pro-Z methyl group at C-25. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 50936-46-4 |
| References: |
| 1. |
Mangla, A.T. and Nes, W.D. Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition. Bioorg. Med. Chem. 8 (2000) 925. [DOI] [PMID: 10882005] |
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| [EC 2.1.1.142 created 2001, modified 2019] |
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