The Enzyme Database

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Accepted name: cycloartenol 24-C-methyltransferase
Reaction: S-adenosyl-L-methionine + cycloartenol = S-adenosyl-L-homocysteine + cyclolaudenol
For diagram of sterol sidechain modification, click here
Glossary: cyclolaudenol = (24S)-24-methylcycloart-25-en-3β-ol
Other name(s): sterol C-methyltransferase
Systematic name: S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase
Comments: S-Adenosyl-L-methionine methylates the Si face of the 24(25)-double bond with elimination of a hydrogen atom from the pro-Z methyl group at C-25.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 50936-46-4
1.  Mangla, A.T. and Nes, W.D. Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition. Bioorg. Med. Chem. 8 (2000) 925. [DOI] [PMID: 10882005]
[EC created 2001, modified 2019]

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