| EC |
2.1.1.171 |
| Accepted name: |
16S rRNA (guanine966-N2)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + guanine966 in 16S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine966 in 16S rRNA |
| Other name(s): |
yhhF (gene name); rsmD (gene name); m2G966 methyltransferase |
| Systematic name: |
S-adenosyl-L-methionine:16S rRNA (guanine966-N2)-methyltransferase |
| Comments: |
The enzyme efficiently methylates guanine966 of the assembled 30S subunits in vitro. Protein-free 16S rRNA is not a substrate for RsmD [1]. The enzyme specifically methylates guanine966 at N2 in 16S rRNA. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Lesnyak, D.V., Osipiuk, J., Skarina, T., Sergiev, P.V., Bogdanov, A.A., Edwards, A., Savchenko, A., Joachimiak, A. and Dontsova, O.A. Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure. J. Biol. Chem. 282 (2007) 5880–5887. [DOI] [PMID: 17189261] |
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| [EC 2.1.1.171 created 1976 as EC 2.1.1.52, part transferred 2010 to EC 2.1.1.171] |
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