| EC |
2.1.1.181 |
| Accepted name: |
23S rRNA (adenine1618-N6)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + adenine1618 in 23S rRNA = S-adenosyl-L-homocysteine + N6-methyladenine1618 in 23S rRNA |
| Other name(s): |
rRNA large subunit methyltransferase F; YbiN protein; rlmF (gene name); m6A1618 methyltransferase |
| Systematic name: |
S-adenosyl-L-methionine:23S rRNA (adenine1618-N6)-methyltransferase |
| Comments: |
The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA [1]. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
| References: |
| 1. |
Sergiev, P.V., Serebryakova, M.V., Bogdanov, A.A. and Dontsova, O.A. The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel. J. Mol. Biol. 375 (2008) 291–300. [DOI] [PMID: 18021804] |
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| [EC 2.1.1.181 created 1976 as EC 2.1.1.48, part transferred 2010 to EC 2.1.1.181] |
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