| EC |
2.1.1.199 |
| Accepted name: |
16S rRNA (cytosine1402-N4)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + cytosine1402 in 16S rRNA = S-adenosyl-L-homocysteine + N4-methylcytosine1402 in 16S rRNA |
| Other name(s): |
RsmH; MraW |
| Systematic name: |
S-adenosyl-L-methionine:16S rRNA (cytosine1402-N4)-methyltransferase |
| Comments: |
RsmH catalyses the N4-methylation of cytosine1402 and RsmI (EC 2.1.1.198) catalyses the 2′-O-methylation of cytosine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Kimura, S. and Suzuki, T. Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA. Nucleic Acids Res. 38 (2010) 1341–1352. [DOI] [PMID: 19965768] |
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| [EC 2.1.1.199 created 2010] |
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