EC |
2.1.1.2 |
Accepted name: |
guanidinoacetate N-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine |
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For diagram of creatine biosynthesis, click here |
Other name(s): |
GA methylpherase; guanidinoacetate methyltransferase; guanidinoacetate transmethylase; methionine-guanidinoacetic transmethylase; guanidoacetate methyltransferase |
Systematic name: |
S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9029-75-8 |
References: |
1. |
Cantoni, G.L. and Scarano, E. The formation of S-adenosylhomocysteine in enzymatic transmethylation reactions. J. Am. Chem. Soc. 76 (1954) 4744. |
2. |
Cantoni, G.L. and Vignos, P.J. Enzymatic mechanism of creatine synthesis. J. Biol. Chem. 209 (1954) 647–659. [PMID: 13192118] |
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[EC 2.1.1.2 created 1961] |
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