ExplorEnz: EC 2.1.1.223

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2.1.1.223

Accepted name:

tRNA₁^Val (adenine³⁷-N⁶)-methyltransferase

Reaction:

S-adenosyl-L-methionine + adenine³⁷ in tRNA₁^Val = S-adenosyl-L-homocysteine + N⁶-methyladenine³⁷ in tRNA₁^Val

Other name(s):

YfiC

Systematic name:

S-adenosyl-L-methionine:tRNA₁^Val (adenine³⁷-N⁶)-methyltransferase

Comments:

The enzyme specifically methylates adenine³⁷ in tRNA₁^Val (anticodon cmo5UAC).

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Golovina, A.Y., Sergiev, P.V., Golovin, A.V., Serebryakova, M.V., Demina, I., Govorun, V.M. and Dontsova, O.A. The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA₁^Val(cmo⁵UAC). RNA 15 (2009) 1134–1141. [DOI] [PMID: 19383770]

[EC 2.1.1.223 created 2011]