| EC |
2.1.1.286 |
| Accepted name: |
25S rRNA (adenine2142-N1)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + adenine2142 in 25S rRNA = S-adenosyl-L-homocysteine + N1-methyladenine2142 in 25S rRNA |
| Other name(s): |
BMT2 (gene name); 25S rRNA m1A2142 methyltransferase |
| Systematic name: |
S-adenosyl-L-methionine:25S rRNA (adenine2142-N1)-methyltransferase |
| Comments: |
In the yeast Saccharomyces cerevisiae this methylation is important for resistance towards hydrogen peroxide and the antibiotic anisomycin. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
| References: |
| 1. |
Sharma, S., Watzinger, P., Kotter, P. and Entian, K.D. Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae. Nucleic Acids Res. 41 (2013) 5428–5443. [DOI] [PMID: 23558746] |
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| [EC 2.1.1.286 created 2013] |
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