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Your query returned 1 entry. 
Printable version
| EC | 2.1.1.316 | ||||
| Accepted name: | mitomycin 6-O-methyltransferase | ||||
| Reaction: | (1) S-adenosyl-L-methionine + 6-demethylmitomycin A = S-adenosyl-L-homocysteine + mitomycin A (2) S-adenosyl-L-methionine + 6-demethylmitomycin B = S-adenosyl-L-homocysteine + mitomycin B |
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| Glossary: | mitomycin A = [(1aS,8S,8aR,8bS)-5-methyl-6,8a-dimethoxy-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2′,3′:3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate mitomycin B = [(1aS,8S,8aR,8bS)-8a-hydroxy-5-methyl-6-methoxy-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2′,3′:3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate |
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| Other name(s): | MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect) | ||||
| Systematic name: | S-adenosyl-L-methionine:6-demethylmitomycin-A 6-O-methyltransferase | ||||
| Comments: | The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B. | ||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||
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