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Your query returned 1 entry. 
Printable version
| EC | 2.1.1.323 | ||
| Accepted name: | (–)-pluviatolide 4-O-methyltransferase | ||
| Reaction: | S-adenosyl-L-methionine + (–)-pluviatolide = S-adenosyl-L-homocysteine + (–)-bursehernin | ||
| For diagram of podophyllotoxin biosynthesis, click here | |||
| Glossary: | (–)-pluviatolide = (3R,4R)-4-(2H-1,3-benzodioxol-5-ylmethyl)-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one (–)-bursehernin = (3R,4R)-4-(2H-1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methyl]oxolan-2-one |
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| Other name(s): | OMT3 (gene name) | ||
| Systematic name: | S-adenosyl-L-methionine:(–)-pluviatolide 4-O-methyltransferase | ||
| Comments: | The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
| References: |
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