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Your query returned 1 entry. 
Printable version
| EC | 2.1.1.324 | ||
| Accepted name: | dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase | ||
| Reaction: | 2 S-adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose = 2 S-adenosyl-L-homocysteine + dTDP-α-D-forosamine (overall reaction) (1a) S-adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose = S-adenosyl-L-homocysteine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose (1b) S-adenosyl-L-methionine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose = S-adenosyl-L-homocysteine + dTDP-α-D-forosamine |
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| For diagram of dTDP-forosamine biosynthesis, click here | |||
| Glossary: | dTDP-α-D-forosamine = dTDP-4-(dimethylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose | ||
| Other name(s): | SpnS; TDP-4-amino-2,3,6-trideoxy-D-glucose N,N-dimethyltransferase | ||
| Systematic name: | S-adenosyl-L-methionine:dTDP-4-amino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose N,N-dimethyltransferase | ||
| Comments: | The enzyme was isolated from the bacterium Saccharopolyspora spinosa, where it is involved in the biosynthesis of spinosyn A, an active ingredient of several commercial insecticides. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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