EC |
2.1.1.380 |
Accepted name: |
3-amino-4-hydroxybenzoate 4-O-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + 3-amino-2,4-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-amino-2-hydroxy-4-methoxybenzoate |
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For diagram of cremeomycin biosynthesis, click here |
Glossary: |
cremeomycin = 6-carboxy-2-diazonio-3-methoxyphenolate |
Other name(s): |
creN (gene name) |
Systematic name: |
S-adenosyl-L-methionine:3-amino-4-hydroxybenzoate 4-O-methyltransferase |
Comments: |
The enzyme, characterized from the bacterium Streptomyces cremeus, is involved in cremeomycin biosynthesis. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Waldman, A.J., Pechersky, Y., Wang, P., Wang, J.X. and Balskus, E.P. The cremeomycin biosynthetic gene cluster encodes a pathway for diazo formation. Chembiochem 16 (2015) 2172–2175. [DOI] [PMID: 26278892] |
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[EC 2.1.1.380 created 2021] |
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