The Enzyme Database

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EC 2.1.1.401     
Accepted name: nicotinate methyltransferase
Reaction: S-adenosyl-L-methionine + nicotinate = S-adenosyl-L-homocysteine + methyl nicotinate
Glossary: methyl nicotinate = nicitinic acid methyl ester
Other name(s): NaMT1
Systematic name: S-adenosyl-L-methionine:nicotinate O-methyltransferase
Comments: The enzyme has been characterized from the plant Arabidopsis thaliana. The product, methyl nicotinate, is involved in the transport of nicotinate to different parts of the plant.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Wu, R., Zhang, F., Liu, L., Li, W., Pichersky, E. and Wang, G. MeNA, controlled by reversible methylation of nicotinate, is an NAD precursor that undergoes long-distance transport in Arabidopsis. Mol. Plant 11 (2018) 1264–1277. [DOI] [PMID: 30055263]
[EC 2.1.1.401 created 2025]
 
 


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