| EC |
2.1.1.79 |
| Accepted name: |
cyclopropane-fatty-acyl-phospholipid synthase |
| Reaction: |
S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid |
| Other name(s): |
cyclopropane synthetase; unsaturated-phospholipid methyltransferase; cyclopropane synthase; cyclopropane fatty acid synthase; cyclopropane fatty acid synthetase; CFA synthase |
| Systematic name: |
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) |
| Comments: |
The enzyme adds a methylene group across the 9,10 position of a Δ9-olefinic acyl chain in phosphatidylethanolamine or, more slowly, phosphatidylglycerol or phosphatidylinositol, forming a cyclopropane derivative (cf. EC 2.1.1.16 methylene-fatty-acyl-phospholipid synthase). |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 51845-48-8 |
| References: |
| 1. |
Chung, A.E. and Law, J.H. Cyclopropane fatty acid synthetase: Partial purification and properties. Biochemistry 3 (1964) 967–974. [PMID: 14214089] |
| 2. |
Zalkin, H., Law, J.H. and Goldfine, H. Enzymatic synthesis of cyclopropane fatty acids catalyzed by bacterial extracts. J. Biol. Chem. 238 (1963) 1242–1248. [PMID: 14003136] |
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| [EC 2.1.1.79 created 1986] |
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