| EC |
2.1.1.99 |
| Accepted name: |
3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + 3-hydroxy-16-methoxy-2,3-dihydrotabersonine = S-adenosyl-L-homocysteine + deacetoxyvindoline |
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For diagram of vindoline biosynthesis, click here |
| Other name(s): |
16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase; NMT; 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase; S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase |
| Systematic name: |
S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase |
| Comments: |
Involved in the biosynthesis of vindoline from tabersonine in the Madagascar periwinkle Catharanthus roseus. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 113478-40-3 |
| References: |
| 1. |
De Luca, V., Balsevich, J., Tyler, R.T., Eilert, U., Panchuk, B.D. and Kurz, W.G.W. Biosynthesis of indole alkaloids - developmental regulation of the biosynthetic-pathway from tabersonine to vindoline in Catharanthus roseus. J. Plant Physiol. 125 (1986) 147–156. |
| 2. |
De Luca, V. and Cutler, A.J. Subcellular localization of enzymes involved in indole alkaloid biosynthesis in Catharanthus roseus. Plant Physiol. 85 (1987) 1099–1102. [PMID: 16665811] |
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| [EC 2.1.1.99 created 1990, modified 2005] |
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