The Enzyme Database

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Accepted name: putrescine carbamoyltransferase
Reaction: carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine
Glossary: putrescine = butane-1,4-diamine
Other name(s): PTCase; putrescine synthase; putrescine transcarbamylase
Systematic name: carbamoyl-phosphate:putrescine carbamoyltransferase
Comments: The plant enzyme also catalyses the reactions of EC ornithine carbamoyltransferase, EC carbamate kinase and EC agmatine deiminase, thus acting as putrescine synthase, converting agmatine [(4-aminobutyl)guanidine] and ornithine into putrescine and citrulline, respectively.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9076-55-5
1.  Roon, R.J. and Barker, H.A. Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase. J. Bacteriol. 109 (1972) 44–50. [PMID: 4621632]
2.  Srivenugopal, K.S. and Adiga, P.R. Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase). J. Biol. Chem. 256 (1981) 9532–9541. [PMID: 6895223]
[EC created 1976]

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