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Your query returned 1 entry. Printable version
EC | 2.3.1.189 | ||||||
Accepted name: | mycothiol synthase | ||||||
Reaction: | desacetylmycothiol + acetyl-CoA = CoA + mycothiol | ||||||
For diagram of mycothiol biosynthesis, click here | |||||||
Glossary: | desacetylmycothiol = 1-O-[2-(L-cysteinamido)-2-deoxy-α-D-glucopyranosyl]-1D-myo-inositol mycothiol = 1-O-[2-(N2-acetyl-L-cysteinamido)-2-deoxy-α-D-glucopyranosyl]-1D-myo-inositol |
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Other name(s): | MshD | ||||||
Systematic name: | acetyl-CoA:desacetylmycothiol O-acetyltransferase | ||||||
Comments: | This enzyme catalyses the last step in the biosynthesis of mycothiol, the major thiol in most actinomycetes, including Mycobacterium [1]. The enzyme is a member of a large family of GCN5-related N-acetyltransferases (GNATs) [2]. The enzyme has been purified from Mycobacterium tuberculosis H37Rv. Acetyl-CoA is the preferred CoA thioester but propionyl-CoA is also a substrate [3]. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||
References: |
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