EC |
2.3.1.20 |
Accepted name: |
diacylglycerol O-acyltransferase |
Reaction: |
acyl-CoA + 1,2-diacyl-sn-glycerol = CoA + triacylglycerol |
Other name(s): |
diglyceride acyltransferase; 1,2-diacylglycerol acyltransferase; diacylglycerol acyltransferase; diglyceride O-acyltransferase; palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase; acyl-CoA:1,2-diacylglycerol O-acyltransferase |
Systematic name: |
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase |
Comments: |
Palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9029-98-5 |
References: |
1. |
Coleman, R. and Bell, R.M. Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols. J. Biol. Chem. 251 (1976) 4537–4543. [PMID: 947894] |
2. |
Grigor, M.R. and Bell, R.M. Separate monoacylglycerol and diacylglycerol acyltransferases function in intestinal triacylglycerol synthesis. Biochim. Biophys. Acta 712 (1982) 464–472. [DOI] [PMID: 6289909] |
3. |
Kawasaki, T. and Snyder, F. Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells. J. Biol. Chem. 263 (1988) 2593–2596. [PMID: 3422635] |
4. |
Weiss, S.B., Kennedy, E.P. and Kiyasu, J.Y. The enzymatic synthesis of triglycerides. J. Biol. Chem. 235 (1960) 40–44. [PMID: 13843753] |
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[EC 2.3.1.20 created 1965] |
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