| EC |
2.3.1.276 |
| Accepted name: |
galactosamine-1-phosphate N-acetyltransferase |
| Reaction: |
acetyl-CoA + α-D-galactosamine 1-phosphate = CoA + N-acetyl-α-D-galactosamine 1-phosphate |
| Other name(s): |
ST0452 (locus name) |
| Systematic name: |
acetyl-CoA:α-D-galactosamine-1-phosphate N-acetyltransferase |
| Comments: |
The enzyme, characterized from the archaeon Sulfolobus tokodaii, is also active toward α-D-glucosamine 1-phosphate (cf. EC 2.3.1.157, glucosamine-1-phosphate N-acetyltransferase). In addition, that enzyme contains a second domain that catalyses the activities of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase, EC 2.7.7.24, glucose-1-phosphate thymidylyltransferase, and EC 2.7.7.83, UDP-N-acetylgalactosamine diphosphorylase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Zhang, Z., Tsujimura, M., Akutsu, J., Sasaki, M., Tajima, H. and Kawarabayasi, Y. Identification of an extremely thermostable enzyme with dual sugar-1-phosphate nucleotidylyltransferase activities from an acidothermophilic archaeon, Sulfolobus tokodaii strain 7. J. Biol. Chem. 280 (2005) 9698–9705. [PMID: 15598657] |
| 2. |
Zhang, Z., Akutsu, J. and Kawarabayasi, Y. Identification of novel acetyltransferase activity on the thermostable protein ST0452 from Sulfolobus tokodaii strain 7. J. Bacteriol. 192 (2010) 3287–3293. [PMID: 20400541] |
| 3. |
Dadashipour, M., Iwamoto, M., Hossain, M.M., Akutsu, J.I., Zhang, Z. and Kawarabayasi, Y. Identification of a direct biosynthetic pathway for UDP-N-acetylgalactosamine from glucosamine-6-phosphate in thermophilic crenarchaeon Sulfolobus tokodaii. J. Bacteriol. 200 (2018) . [PMID: 29507091] |
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| [EC 2.3.1.276 created 2018] |
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