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Your query returned 1 entry. 
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| EC | 2.3.1.279 | ||
| Accepted name: | long-chain-acyl-CoA—trehalose acyltransferase | ||
| Reaction: | a long-chain-fatty acyl-CoA + α,α-trehalose = a 2-(long-chain-fatty acyl)-trehalose + CoA | ||
| Glossary: | polyacyltrehalose = PAT = a 2-(long-chain-fatty acyl)-2′,3,4′,6-tetramycolipenoyl-trehalose a mycolipenoyl-CoA = a (2E,2S,4S,6S)-2,4,6-trimethyl-2-enoyl-CoA |
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| Other name(s): | papA3 (gene name) | ||
| Systematic name: | long-chain-fatty acyl-CoA:α,α-trehalose 2-acyltransferase | ||
| Comments: | The enzyme, characterized from the bacterium Mycobacterium tuberculosis, participates in the biosynthesis of polyacyltrehalose (PAT), a pentaacylated, trehalose-based glycolipid found in the cell wall of pathogenic strains. The enzyme catalyses two successive activities - it first transfers an acyl (often palmitoyl) group to position 2, followed by the transfer of a mycolipenyl group to position 3 (see EC 2.3.1.278, mycolipenoyl-CoA—2-(long-chain-fatty acyl)-trehalose mycolipenoyltransferase). | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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