The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: (aminoalkyl)phosphonate N-acetyltransferase
Reaction: acetyl-CoA + (aminomethyl)phosphonate = CoA + (acetamidomethyl)phosphonate
Other name(s): phnO (gene name)
Systematic name: acetyl-CoA:(aminomethyl)phosphonate N-acetyltransferase
Comments: The enzyme, characterized from the bacterium Escherichia coli, is able to acetylate a range of (aminoalkyl)phosphonic acids. Requires a divalent metal ion for activity.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Errey, J.C. and Blanchard, J.S. Functional annotation and kinetic characterization of PhnO from Salmonella enterica. Biochemistry 45 (2006) 3033–3039. [PMID: 16503658]
2.  Hove-Jensen, B., McSorley, F.R. and Zechel, D.L. Catabolism and detoxification of 1-aminoalkylphosphonic acids: N-acetylation by the phnO gene product. PLoS One 7:e46416 (2012). [PMID: 23056305]
[EC created 2018]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald