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Your query returned 1 entry. Printable version
EC | 2.3.1.296 | ||
Accepted name: | ω-hydroxyceramide transacylase | ||
Reaction: | a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain ω-hydroxyceramide = a diacyl-sn-glycerol + a linoleate-esterified acylceramide | ||
Glossary: | an ultra-long-chain fatty acid = ULCFA = a fatty acid with aliphatic chain of 28 or more carbons an ultra-long-chain ω-hydroxyceramide = a ceramide that contains an ultra-long-chain ω-hydroxyfatty acid moiety (C28-C36) acylceramide = ω-O-acylceramide = a ceramide that contains an ultra-long-chain ω-hydroxyfatty acid moiety (C28-C36) that is further extended by ω-esterification with linoleic acid. |
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Other name(s): | PNPLA1 (gene name) | ||
Systematic name: | triacyl-sn-glycerol:ultra-long-chain ω-hydroxyceramide ω-O-linoleoyltransferase | ||
Comments: | The enzyme participates in the production of acylceramides in the stratum corneum, the outermost layer of the epidermis. Acylceramides are crucial components of the skin permeability barrier. | ||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc | ||
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