| EC |
2.3.1.306 |
| Accepted name: |
acetyl-CoA:lysine N6-acetyltransferase |
| Reaction: |
acetyl-CoA + L-lysine = CoA + N6-acetyl-L-lysine |
| Other name(s): |
LYC1 (gene name); lysine N6-acetyltransferase (ambiguous) |
| Systematic name: |
acetyl-CoA:L-lysine N6-acetyltransferase |
| Comments: |
The enzyme catalyses the first step of an L-lysine degradation pathway found in many fungal species. The enzyme is specific for acetyl-CoA as the acetyl donor. cf. EC 2.3.1.32, lysine N-acetyltransferase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Schmidt, H., Bode, R., and Birnbaum , D. Lysine degradation in Candida maltosa: occurrence of a novel enzyme, acetyl-CoA: L-lysine N-acetyltransferase. Arch. Microbiol. 150 (1988) 215–218. [DOI] |
| 2. |
Large, P.J. and Robertson, A. The route of lysine breakdown in Candida tropicalis. FEMS Microbiol. Lett. 66 (1991) 209–213. [DOI] [PMID: 1682209] |
| 3. |
Bode, R., Thurau, A.M. and Schmidt, H. Characterization of acetyl-CoA: L-lysine N6-acetyltransferase, which catalyses the first step of carbon catabolism from lysine in Saccharomyces cerevisiae. Arch. Microbiol. 160 (1993) 397–400. [DOI] [PMID: 8257283] |
| 4. |
Beckerich, J.M., Lambert, M. and Gaillardin, C. LYC1 is the structural gene for lysine N-6-acetyl transferase in yeast. Curr. Genet. 25 (1994) 24–29. [DOI] [PMID: 8082161] |
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| [EC 2.3.1.306 created 2021] |
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