The Enzyme Database

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Accepted name: acetyl-CoA:lysine N6-acetyltransferase
Reaction: acetyl-CoA + L-lysine = CoA + N6-acetyl-L-lysine
Other name(s): LYC1 (gene name); lysine N6-acetyltransferase (ambiguous)
Systematic name: acetyl-CoA:L-lysine N6-acetyltransferase
Comments: The enzyme catalyses the first step of an L-lysine degradation pathway found in many fungal species. The enzyme is specific for acetyl-CoA as the acetyl donor. cf. EC, lysine N-acetyltransferase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Schmidt, H., Bode, R., and Birnbaum , D. Lysine degradation in Candida maltosa: occurrence of a novel enzyme, acetyl-CoA: L-lysine N-acetyltransferase. Arch. Microbiol. 150 (1988) 215–218. [DOI]
2.  Large, P.J. and Robertson, A. The route of lysine breakdown in Candida tropicalis. FEMS Microbiol. Lett. 66 (1991) 209–213. [DOI] [PMID: 1682209]
3.  Bode, R., Thurau, A.M. and Schmidt, H. Characterization of acetyl-CoA: L-lysine N6-acetyltransferase, which catalyses the first step of carbon catabolism from lysine in Saccharomyces cerevisiae. Arch. Microbiol. 160 (1993) 397–400. [DOI] [PMID: 8257283]
4.  Beckerich, J.M., Lambert, M. and Gaillardin, C. LYC1 is the structural gene for lysine N-6-acetyl transferase in yeast. Curr. Genet. 25 (1994) 24–29. [DOI] [PMID: 8082161]
[EC created 2021]

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