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Your query returned 1 entry.
Printable version
| EC | 2.3.1.325 | ||
| Accepted name: | 17,18-epoxy-17-hydroxycur-19-ene N-malonyltransferase | ||
| Reaction: | malonyl-CoA + 17,18-epoxy-17-hydroxycur-19-ene = CoA + prestrychnine | ||
| Glossary: | 17,18-epoxy-17-hydroxycur-19-ene = (19E)-18-hydroxycur-19-en-17-al = Wieland-Gumlich aldehyde prestrychnine = 3-(17,18-epoxy-17-hydroxycur-19-en-1-yl)-3-oxopropanoic acid |
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| Other name(s): | Wieland-Gumlich aldehyde N-malonyltransferase | ||
| Systematic name: | malonyl-CoA:17,18-epoxy-17-hydroxycur-19-ene N-malonyltransferase | ||
| Comments: | The enzyme, characterized from the tree Strychnos nux-vomica, catalyses the last step in the biosynthesis of strychnine. The product, prestrychnine, undergoes a slow spontaneous decarboxylation and cyclization, forming strychnine. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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