The Enzyme Database

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Accepted name: glutathione γ-glutamylcysteinyltransferase
Reaction: glutathione + [Glu(-Cys)]n-Gly = Gly + [Glu(-Cys)]n+1-Gly
Other name(s): phytochelatin synthase; γ-glutamylcysteine dipeptidyl transpeptidase
Systematic name: glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 125390-02-5
1.  Grill, E., Löffler, S., Winnacker, E.-L. and Zenk, M.H. Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase). Proc. Natl. Acad. Sci. USA 86 (1989) 6838–6842. [DOI] [PMID: 16594069]
[EC created 1992]

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