EC |
2.4.1.331 |
Accepted name: |
8-demethyltetracenomycin C L-rhamnosyltransferase |
Reaction: |
dTDP-β-L-rhamnose + 8-demethyltetracenomycin C = dTDP + 8-demethyl-8-α-L-rhamnosyltetracenomycin C |
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For diagram of elloramycin biosynthesis, click here |
Glossary: |
dTDP-β-L-rhamnose = dTDP-6-deoxy-β-L-mannose |
Other name(s): |
elmGT |
Systematic name: |
dTDP-β-L-rhamnose:8-demethyltetracenomycin C 3-α-L-rhamnosyltransferase |
Comments: |
Isolated from Streptomyces olivaceus Tü2353. Involved in elloramycin biosynthesis. In vitro it can also utilize other 6-deoxy D- or L-hexoses. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Blanco, G., Patallo, E.P., Brana, A.F., Trefzer, A., Bechthold, A., Rohr, J., Mendez, C. and Salas, J.A. Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin. Chem. Biol. 8 (2001) 253–263. [DOI] [PMID: 11306350] |
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[EC 2.4.1.331 created 2014] |
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