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Your query returned 1 entry. Printable version
EC | 2.4.99.23 | ||||||||||
Accepted name: | lipopolysaccharide heptosyltransferase I | ||||||||||
Reaction: | ADP-L-glycero-β-D-manno-heptose + an α-Kdo-(2→4)-α-Kdo-(2→6)-[lipid A] = ADP + an α-Hep-(1→5)-[α-Kdo-(2→4)]-α-Kdo-(2→6)-[lipid A] | ||||||||||
Glossary: | Lipid A is a lipid component of the lipopolysaccharides (LPS) of Gram-negative bacteria. It consists of two glucosamine units connected by a β(1→6) bond and decorated with four to seven acyl chains and up to two phosphate groups. Hep = L-glycero-D-manno-heptose |
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Other name(s): | HepI; rfaC (gene name); WaaC; heptosyltransferase I (ambiguous) | ||||||||||
Systematic name: | ADP-L-glycero-β-D-manno-heptose:an α-Kdo-(2→4)-α-Kdo-(2→6)-[lipid A] 5-α-heptosyltransferase | ||||||||||
Comments: | The enzyme catalyses a glycosylation step in the biosynthesis of the inner core oligosaccharide of the lipopolysaccharide (endotoxin) of many Gram-negative bacteria. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||
References: |
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