The Enzyme Database

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Accepted name: 7,8-dihydropterin-6-yl-methyl-4-(β-D-ribofuranosyl)aminobenzene 5′-phosphate synthase
Reaction: (7,8-dihydropterin-6-yl)methyl diphosphate + 4-(β-D-ribofuranosyl)aniline 5′-phosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(β-D-ribofuranosyl)aniline 5′-phosphate + diphosphate
For diagram of methanopterin biosynthesis (part 2), click here
Other name(s): MJ0301 (gene name); dihydropteroate synthase (ambiguous)
Systematic name: (7,8-dihydropterin-6-yl)methyl-diphosphate:4-(β-D-ribofuranosyl)aniline 5′-phosphate 6-hydroxymethyl-7,8-dihydropterintransferase
Comments: The enzyme, which has been studied in the archaeon Methanocaldococcus jannaschii, is involved in the biosynthesis of tetrahydromethanopterin.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Xu, H., Aurora, R., Rose, G.D. and White, R.H. Identifying two ancient enzymes in Archaea using predicted secondary structure alignment. Nat. Struct. Biol. 6 (1999) 750–754. [DOI] [PMID: 10426953]
[EC created 2013]

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