EC |
2.5.1.134 |
Accepted name: |
cystathionine β-synthase (O-acetyl-L-serine) |
Reaction: |
O-acetyl-L-serine + L-homocysteine = L-cystathionine + acetate |
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For diagram of O3-Acetyl-L-serine metabolism, click here |
Other name(s): |
MccB; O-acetylserine dependent cystathionine β-synthase |
Systematic name: |
O-acetyl-L-serine:L-homocysteine 2-amino-2-carboxyethyltransferase |
Comments: |
A pyridoxal 5′-phosphate protein. The enzyme, purified from the bacterium Bacillus subtilis, also has a low activity with L-serine (cf. EC 4.2.1.22, cystathionine β-synthase). |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
References: |
1. |
Hullo, M.F., Auger, S., Soutourina, O., Barzu, O., Yvon, M., Danchin, A. and Martin-Verstraete, I. Conversion of methionine to cysteine in Bacillus subtilis and its regulation. J. Bacteriol. 189 (2007) 187–197. [DOI] [PMID: 17056751] |
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[EC 2.5.1.134 created 2016] |
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