ExplorEnz: EC 2.5.1.144

Your query returned 1 entry. Printable version

2.5.1.144

Accepted name:

S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent)

Reaction:

O-acetyl-L-serine + thiosulfate = S-sulfo-L-cysteine + acetate

For diagram of O³-Acetyl-L-serine metabolism, click here

Glossary:

O-acetyl-L-serine = (2S)-3-acetyloxy-2-aminopropanoic acid

Other name(s):

cysteine synthase B; cysM (gene name); CS26 (gene name)

Systematic name:

O-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase

Comments:

In plants, the activity is catalysed by a chloroplastic enzyme that plays an important role in chloroplast function and is essential for light-dependent redox regulation within the chloroplast. The bacterial enzyme also catalyses the activity of EC 2.5.1.47, cysteine synthase. cf. EC 2.8.5.1, S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent).

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB

References:

1.	Hensel, G. and Truper, H.G. O-Acetylserine sulfhydrylase and S-sulfocysteine synthase activities of Rhodospirillum tenue. Arch. Microbiol. 134 (1983) 227–232. [PMID: 6615127]
2.	Nakamura, T., Iwahashi, H. and Eguchi, Y. Enzymatic proof for the identity of the S-sulfocysteine synthase and cysteine synthase B of Salmonella typhimurium. J. Bacteriol. 158 (1984) 1122–1127. [PMID: 6373737]
3.	Bermudez, M.A., Paez-Ochoa, M.A., Gotor, C. and Romero, L.C. Arabidopsis S-sulfocysteine synthase activity is essential for chloroplast function and long-day light-dependent redox control. Plant Cell 22 (2010) 403–416. [DOI] [PMID: 20179139]
4.	Bermudez, M.A., Galmes, J., Moreno, I., Mullineaux, P.M., Gotor, C. and Romero, L.C. Photosynthetic adaptation to length of day is dependent on S-sulfocysteine synthase activity in the thylakoid lumen. Plant Physiol. 160 (2012) 274–288. [DOI] [PMID: 22829322]
5.	Gotor, C. and Romero, L.C. S-Sulfocysteine synthase function in sensing chloroplast redox status. Plant Signal. Behav. 8:e23313 (2013). [DOI] [PMID: 23333972]

[EC 2.5.1.144 created 2018]