| EC |
2.5.1.2 |
| Accepted name: |
thiamine pyridinylase |
| Reaction: |
thiamine + pyridine = 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium + 4-methyl-5-(2-hydroxyethyl)thiazole |
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For diagram of reaction, click here |
| Other name(s): |
pyrimidine transferase; thiaminase I; thiamin hydrolase; thiamin pyridinolase; thiaminase (ambiguous); thiamine pyridinolase; thiamin pyridinylase; thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase |
| Systematic name: |
thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase |
| Comments: |
Various bases and thiol compounds can act instead of pyridine. |
| Links to other databases: |
BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9030-35-7 |
| References: |
| 1. |
Fujita, A. Thiaminases. Adv. Enzymol. Relat. Subj. Biochem. 15 (1954) 389–421. [PMID: 13158184] |
| 2. |
Kenten, R.H. The partial purification and properties of a thiaminase from bracken [Pteridium aquilinum (L.) Kuhn] Biochem. J. 67 (1957) 25–33. [PMID: 13471505] |
| 3. |
Wittliff, J.L. and Airth, R.L. The extracellular thiaminase I of Bacillus thiaminolyticus. I. Purification and physicochemical properties. Biochemistry 7 (1968) 736–744. [PMID: 4966932] |
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| [EC 2.5.1.2 created 1961, modified 1976, modified 2001] |
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