| EC |
2.5.1.26 |
| Accepted name: |
alkylglycerone-phosphate synthase |
| Reaction: |
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion |
| Glossary: |
a long-chain alcohol = an alcohol derived from a fatty acid with an aliphatic chain of 13-22 carbons.
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| Other name(s): |
alkyldihydroxyacetonephosphate synthase; alkyldihydroxyacetone phosphate synthetase; alkyl DHAP synthetase; alkyl-DHAP; dihydroxyacetone-phosphate acyltransferase (ambiguous); DHAP-AT |
| Systematic name: |
1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase |
| Comments: |
The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 64060-42-0, 102484-74-2 |
| References: |
| 1. |
Brown, A.J. and Snyder, F. Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism. J. Biol. Chem. 257 (1982) 8835–8839. [PMID: 7096336] |
| 2. |
Wykle, R.L., Piantadosi, C. and Snyder, F. The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor. J. Biol. Chem. 247 (1972) 2944–2948. [PMID: 4401994] |
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| [EC 2.5.1.26 created 1984] |
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