| EC |
2.5.1.29 |
| Accepted name: |
geranylgeranyl diphosphate synthase |
| Reaction: |
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate |
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For diagram of terpenoid biosynthesis, click here |
| Other name(s): |
geranylgeranyl-diphosphate synthase; geranylgeranyl pyrophosphate synthetase; geranylgeranyl-PP synthetase; farnesyltransferase; geranylgeranyl pyrophosphate synthase; farnesyltranstransferase (obsolete) |
| Systematic name: |
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase |
| Comments: |
Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9032-58-0 |
| References: |
| 1. |
Sagami, H., Ishi, K. and Ogura, K. Occurrence and unusual properties of geranylgeranyl pyrophosphate synthetase of pig liver. Biochem. Int. 3 (1981) 669–675. |
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| [EC 2.5.1.29 created 1984, modified 2011] |
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