| EC |
2.5.1.51 |
| Accepted name: |
β-pyrazolylalanine synthase |
| Reaction: |
O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate |
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For diagram of O3-Acetyl-L-serine metabolism, click here |
| Glossary: |
O-acetyl-L-serine = (2S)-3-acetyloxy-2-aminopropanoic acid
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| Other name(s): |
β-(1-pyrazolyl)alanine synthase; β-pyrazolealanine synthase; β-pyrazolylalanine synthase (acetylserine); O3-acetyl-L-serine acetate-lyase (adding pyrazole); BPA-synthase; pyrazolealanine synthase; pyrazolylalaninase; 3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase; O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase |
| Systematic name: |
O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase |
| Comments: |
The enzyme is highly specific for acetylserine and pyrazole. Not identical with EC 2.5.1.52 L-mimosine synthase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37290-81-6 |
| References: |
| 1. |
Murakoshi, I., Ikegami, F., Hinuma, Y. and Hanma, Y. Purification and characterization of β-(pyrazol-1-yl)-L-alanine synthase from Citrullus vulgaris. Phytochemistry 23 (1984) 973–977. |
| 2. |
Murakoshi, I., Ikegami, F., Hinuma, Y. and Hanma, Y. Purification and characterization of L-mimosine synthase from Leucaena leucocephala. Phytochemistry 23 (1984) 1905–1908. |
| 3. |
Murakoshi, I., Kuramoto, H. and Haginiwa, J. The enzymic synthesis of β-substituted alanines. Phytochemistry 11 (1972) 177–182. |
| 4. |
Noji, M., Murakoshi, I. and Saito, K. Evidence for identity of β-pyrazolealanine synthase with cysteine synthase in watermelon: formation of β-pyrazole-alanine by cloned cysteine synthase in vitro and in vivo. Biochem. Biophys. Res. Commun. 197 (1993) 1111–1117. [DOI] [PMID: 8280125] |
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| [EC 2.5.1.51 created 1989 as EC 4.2.99.14 (EC 4.2.99.17 incorporated 1992), transferred 2002 to EC 2.5.1.51] |
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