| EC |
2.5.1.62 |
| Accepted name: |
chlorophyll synthase |
| Reaction: |
chlorophyllide a + phytyl diphosphate = chlorophyll a + diphosphate |
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For diagram of the later stages of chlorophyll biosynthesis, click here |
| Systematic name: |
chlorophyllide-a:phytyl-diphosphate phytyltransferase |
| Comments: |
Requires Mg2+. The enzyme is modified by binding of the first substrate, phytyl diphosphate, before reaction of the modified enzyme with the second substrate, chlorophyllide a, can occur. The reaction also occurs when phytyl diphosphate is replaced by geranylgeranyl diphosphate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9077-08-1 |
| References: |
| 1. |
Schmid, H.C., Rassadina, V., Oster, U., Schoch, S. and Rüdiger, W. Pre-loading of chlorophyll synthase with tetraprenyl diphosphate is an obligatory step in chlorophyll biosynthesis. Biol. Chem. 383 (2002) 1769–1778. [DOI] [PMID: 12530542] |
| 2. |
Oster, U., Bauer, C.E. and Rüdiger, W. Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli. J. Biol. Chem. 272 (1997) 9671–9676. [DOI] [PMID: 9092496] |
| 3. |
Rüdiger, W., Benz, J. and Guthoff, C. Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes. Eur. J. Biochem. 109 (1980) 193–200. [DOI] [PMID: 7408876] |
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| [EC 2.5.1.62 created 2003] |
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