EC |
2.6.1.110 |
Accepted name: |
dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase |
Reaction: |
dTDP-4-amino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose + 2-oxoglutarate = dTDP-4-dehydro-2,3,6-trideoxy-α-D-hexopyranose + L-glutamate |
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For diagram of dTDP-forosamine biosynthesis, click here |
Other name(s): |
SpnR; TDP-4-keto-2,3,6-trideoxy-D-glucose 4-aminotransferase |
Systematic name: |
dTDP-4-amino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranose:2-oxoglutarate aminotransferase |
Comments: |
A pyridoxal-phosphate protein. The enzyme, isolated from the bacterium Saccharopolyspora spinosa, participates in the biosynthesis of forosamine. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Hong, L., Zhao, Z., Melancon, C.E., 3rd, Zhang, H. and Liu, H.W. In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa. J. Am. Chem. Soc. 130 (2008) 4954–4967. [DOI] [PMID: 18345667] |
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[EC 2.6.1.110 created 2016] |
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