The Enzyme Database

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EC 2.6.1.120     
Accepted name: β-alanine—2-oxoglutarate transaminase
Reaction: β-alanine + 2-oxoglutarate = 3-oxopropanoate + L-glutamate
Other name(s): pydD (gene name); β-alanine aminotransferase
Systematic name: β-alanine:2-oxoglutarate aminotransferase
Comments: The enzyme, found in many Gram-positive bacteria, participates in the reductive degradation of pyrimidines. In eukaryotes this activity is catalysed by EC 2.6.1.19, 4-aminobutyrate—2-oxoglutarate transaminase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Fujimoto, S., Mizutani, N., Mizota, C. and Tamaki, N. The level of β-alanine aminotransferase activity in regenerating and differentiating rat liver. Biochim. Biophys. Acta 882 (1986) 106–112. [DOI] [PMID: 3085724]
2.  Yin, J., Wei, Y., Liu, D., Hu, Y., Lu, Q., Ang, E.L., Zhao, H. and Zhang, Y. An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine. J. Biol. Chem. 294 (2019) 15662–15671. [DOI] [PMID: 31455636]
[EC 2.6.1.120 created 2021]
 
 


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