The Enzyme Database

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Accepted name: tryptophan—phenylpyruvate transaminase
Reaction: L-tryptophan + phenylpyruvate = (indol-3-yl)pyruvate + L-phenylalanine
For diagram of reaction, click here and for mechanism, click here
Other name(s): L-tryptophan-α-ketoisocaproate aminotransferase
Systematic name: L-tryptophan:phenylpyruvate aminotransferase
Comments: Valine, leucine and isoleucine can replace tryptophan as amino donor.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 37277-87-5
1.  Koide, Y., Honma, M. and Shimomura, T. L-Tryptophan-α-ketoisocaproate aminotransferase from Pseudomonas sp. Agric. Biol. Chem. 44 (1980) 2013–2019.
2.  Sukanya, N.K. and Vaidyanathan, C.S. Aminotransferases of Agrobacterium tumefaciens. Transamination between tryptophan and phenylpyruvate. Biochem. J. 92 (1964) 594–598. [PMID: 5837443]
[EC created 1972]

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