| EC |
2.6.1.51 |
| Accepted name: |
serine—pyruvate transaminase |
| Reaction: |
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine |
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For diagram of reaction, click here and for mechanism, click here |
| Other name(s): |
SPT; hydroxypyruvate:L-alanine transaminase |
| Systematic name: |
L-serine:pyruvate aminotransferase |
| Comments: |
A pyridoxal-phosphate protein. The liver enzyme may be identical with EC 2.6.1.44 alanine-glyoxylate transaminase. |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9030-88-0 |
| References: |
| 1. |
Cheung, G.P., Rosenblum, I. and Sallach, H.J. Comparative studies of enzymes related to serine metabolism in higher plants. Plant Physiol. 43 (1968) 1813–1820. [PMID: 5699148] |
| 2. |
Kretovich, V.L. and Stepanovich, K.M. [The synthesis of serine from hydroxypyruvate in plants.] Dokl. Akad. Nauk S.S.S.R. 139 (1961) 488–490. (in Russian) |
| 3. |
Sallach, H.J. Formation of serine from hydroxypyruvate and L-alanine. J. Biol. Chem. 223 (1956) 1101–1108. [PMID: 13385257] |
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| [EC 2.6.1.51 created 1972] |
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