The Enzyme Database

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Accepted name: aromatic-amino-acid transaminase
Reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate
For diagram of phenylalanine and tyrosine biosynthesis, click here and for diagram of the methionine-salvage pathway, click here
Other name(s): aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT
Systematic name: aromatic-amino-acid:2-oxoglutarate aminotransferase
Comments: A pyridoxal-phosphate protein. L-Methionine can also act as donor, but more slowly; oxaloacetate can act as acceptor. Controlled proteolysis converts the enzyme into EC aspartate transaminase.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37332-38-0
1.  Mavrides, C. and Orr, W. Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli. J. Biol. Chem. 250 (1975) 4128–4133. [PMID: 236311]
[EC created 1976]

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