| EC |
2.6.1.57 |
| Accepted name: |
aromatic-amino-acid transaminase |
| Reaction: |
an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate |
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For diagram of phenylalanine and tyrosine biosynthesis, click here and for diagram of the methionine-salvage pathway, click here |
| Other name(s): |
aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT |
| Systematic name: |
aromatic-amino-acid:2-oxoglutarate aminotransferase |
| Comments: |
A pyridoxal-phosphate protein. L-Methionine can also act as donor, but more slowly; oxaloacetate can act as acceptor. Controlled proteolysis converts the enzyme into EC 2.6.1.1 aspartate transaminase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37332-38-0 |
| References: |
| 1. |
Mavrides, C. and Orr, W. Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli. J. Biol. Chem. 250 (1975) 4128–4133. [PMID: 236311] |
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| [EC 2.6.1.57 created 1976] |
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