| EC |
2.6.1.58 |
| Accepted name: |
phenylalanine(histidine) transaminase |
| Reaction: |
L-phenylalanine + pyruvate = phenylpyruvate + L-alanine |
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For diagram of reaction, click here and for mechanism, click here |
| Other name(s): |
phenylalanine (histidine) aminotransferase; phenylalanine(histidine):pyruvate aminotransferase; histidine:pyruvate aminotransferase; L-phenylalanine(L-histidine):pyruvate aminotransferase |
| Systematic name: |
L-phenylalanine:pyruvate aminotransferase |
| Comments: |
L-Histidine and L-tyrosine can act instead of L-phenylalanine; in the reverse reaction, L-methionine, L-serine and L-glutamine can replace L-alanine. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 72560-98-6 |
| References: |
| 1. |
Minatogawa, Y., Noguchi, T. and Kido, R. Species distribution and properties of hepatic phenylalanine (histidine):pyruvate aminotransferase. Hoppe-Seyler's Z. Physiol. Chem. 358 (1977) 59–67. [PMID: 14070] |
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| [EC 2.6.1.58 created 1978] |
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