The Enzyme Database

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Accepted name: phenylalanine(histidine) transaminase
Reaction: L-phenylalanine + pyruvate = phenylpyruvate + L-alanine
For diagram of reaction, click here and for mechanism, click here
Other name(s): phenylalanine (histidine) aminotransferase; phenylalanine(histidine):pyruvate aminotransferase; histidine:pyruvate aminotransferase; L-phenylalanine(L-histidine):pyruvate aminotransferase
Systematic name: L-phenylalanine:pyruvate aminotransferase
Comments: L-Histidine and L-tyrosine can act instead of L-phenylalanine; in the reverse reaction, L-methionine, L-serine and L-glutamine can replace L-alanine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 72560-98-6
1.  Minatogawa, Y., Noguchi, T. and Kido, R. Species distribution and properties of hepatic phenylalanine (histidine):pyruvate aminotransferase. Hoppe-Seyler's Z. Physiol. Chem. 358 (1977) 59–67. [PMID: 14070]
[EC created 1978]

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