EC |
2.7.1.114 |
Accepted name: |
AMP—thymidine kinase |
Reaction: |
AMP + thymidine = adenosine + dTMP |
Glossary: |
dTMP = thymidine 5′-phosphate |
Other name(s): |
adenylate-nucleoside phosphotransferase |
Systematic name: |
AMP:thymidine 5′-phosphotransferase |
Comments: |
The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyses this reaction as well as those of EC 2.7.1.21 (thymidine kinase), EC 2.7.1.118 (ADP—thymidine kinase) and EC 2.7.4.9 (dTMP kinase). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 60440-28-0 |
References: |
1. |
Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase. Biochim. Biophys. Acta 708 (1982) 99–103. [DOI] [PMID: 6293576] |
2. |
Falke, D., Nehrbass, W., Brauer, D. and Mueller, W.E.G. Adenylic acid: deoxythymidine 5′-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme. J. Gen. Virol. 53 (1981) 247–255. [DOI] [PMID: 6267178] |
|
[EC 2.7.1.114 created 1984] |
|
|
|
|