The Enzyme Database

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EC 2.7.1.114     
Accepted name: AMP—thymidine kinase
Reaction: AMP + thymidine = adenosine + dTMP
Glossary: dTMP = thymidine 5′-phosphate
Other name(s): adenylate-nucleoside phosphotransferase
Systematic name: AMP:thymidine 5′-phosphotransferase
Comments: The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyses this reaction as well as those of EC 2.7.1.21 (thymidine kinase), EC 2.7.1.118 (ADP—thymidine kinase) and EC 2.7.4.9 (dTMP kinase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 60440-28-0
References:
1.  Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase. Biochim. Biophys. Acta 708 (1982) 99–103. [DOI] [PMID: 6293576]
2.  Falke, D., Nehrbass, W., Brauer, D. and Mueller, W.E.G. Adenylic acid: deoxythymidine 5′-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme. J. Gen. Virol. 53 (1981) 247–255. [DOI] [PMID: 6267178]
[EC 2.7.1.114 created 1984]
 
 


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