| EC |
2.7.1.140 |
| Accepted name: |
inositol-tetrakisphosphate 5-kinase |
| Reaction: |
ATP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate |
| Other name(s): |
1D-myo-inositol-tetrakisphosphate 5-kinase |
| Systematic name: |
ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase |
| Comments: |
The enzyme from plants and yeast can also use Ins(1,2,3,4,6)P5 as a substrate [2]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 123940-40-9 |
| References: |
| 1. |
Shears, S.B. The pathway of myo-inositol 1,3,4-trisphosphate phosphorylation in liver. Identification of myo-inositol 1,3,4-trisphosphate 6-kinase, myo-inositol 1,3,4-trisphosphate 5-kinase, and myo-inositol 1,3,4,6-tetrakisphosphate 5-kinase. J. Biol. Chem. 264 (1989) 19879–19886. [PMID: 2584198] |
| 2. |
Stevenson-Paulik, J., Odom, A.R. and York, J.D. Molecular and biochemical characterization of two plant inositol
polyphosphate 6-/3-/5-kinases. J. Biol. Chem. 277 (2002) 42711–42718. [DOI] [PMID: 12226109] |
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| [EC 2.7.1.140 created 1992] |
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