| EC |
2.7.1.143 |
| Accepted name: |
diphosphate-purine nucleoside kinase |
| Reaction: |
diphosphate + a purine nucleoside = phosphate + a purine mononucleotide |
| Other name(s): |
pyrophosphate-purine nucleoside kinase |
| Systematic name: |
diphosphate:purine nucleoside phosphotransferase |
| Comments: |
The enzyme from the Acholeplasma class of Mollicutes catalyses the conversion of adenosine, guanosine and inosine to AMP, GMP and IMP. ATP cannot substitute for diphosphate as a substrate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 70356-41-1 |
| References: |
| 1. |
Tryon, V.V., Pollack, D. Purine metabolism in Acholeplasma laidlawii B: novel PPi-dependent nucleoside kinase activity. J. Bacteriol. 159 (1984) 265–270. [PMID: 6330034] |
| 2. |
Tryon, V.V., Pollack, J.D. Distinctions in Mollicutes purine metabolism: pyrophosphate-dependent nucleoside kinase and dependence on guanylate salvage. Int. J. Systematic Bacteriol. 35 (1985) 497–501. |
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| [EC 2.7.1.143 created 1999] |
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