| EC |
2.7.1.146 |
| Accepted name: |
ADP-specific phosphofructokinase |
| Reaction: |
ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate |
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For diagram of glycolysis, click here |
| Other name(s): |
ADP-6-phosphofructokinase; ADP-dependent phosphofructokinase |
| Systematic name: |
ADP:D-fructose-6-phosphate 1-phosphotransferase |
| Comments: |
ADP can be replaced by GDP, ATP and GTP, to a limited extent. Divalent cations are necessary for activity, with Mg2+ followed by Co2+ being the most effective. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 237739-62-7 |
| References: |
| 1. |
Tuininga, J.E., Verhees, C.H., van der Oost, J., Kengen, S.W., Stams, A.J. and de Vos, W.M. Molecular and biochemical characterization of the ADP-dependent phosphofructokinase from the hyperthermophilic archaeon Pyrococcus furiosus. J. Biol. Chem. 274 (1999) 21023–21028. [DOI] [PMID: 10409652] |
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| [EC 2.7.1.146 created 2001] |
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