| EC |
2.7.1.149 |
| Accepted name: |
1-phosphatidylinositol-5-phosphate 4-kinase |
| Reaction: |
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
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For diagram of 1-phosphatidyl-myo-inositol metabolism (part 2), click here |
| Glossary: |
1-phosphatidyl-1D-myo-inositol 5-phosphate = PtdIns5P
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = PtdIns(4,5)P2 |
| Other name(s): |
type II PIP kinase |
| Systematic name: |
ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 247907-17-1 |
| References: |
| 1. |
Rameh, L.E., Tolias, K.F., Duckworth, B.C. and Cantley, L.C. A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. Nature 390 (1997) 192–196. [DOI] [PMID: 9367159] |
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| [EC 2.7.1.149 created 2002] |
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