ExplorEnz: EC 2.7.1.150

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2.7.1.150

Accepted name:

1-phosphatidylinositol-3-phosphate 5-kinase

Reaction:

ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate

For diagram of 1-phosphatidyl-myo-inositol metabolism, click here

Glossary:

1-phosphatidyl-1D-myo-inositol 3-phosphate = PtdIns3P
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate = PtdIns(3,5)P₂

Other name(s):

type III PIP kinase; phosphatidylinositol 3-phosphate 5-kinase

Systematic name:

ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB

References:

1.	Cooke, F.T., Dove, S.K., McEwen, R.K., Painter, G., Holmes, A.B., Hall, M.N., Michell, R.H. and Parker, P.J. The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Curr. Biol. 9 (1998) 1219–1222. [DOI] [PMID: 9811604]

[EC 2.7.1.150 created 2002]