| EC |
2.7.1.188 |
| Accepted name: |
2-epi-5-epi-valiolone 7-kinase |
| Reaction: |
ATP + 2-epi-5-epi-valiolone = ADP + 2-epi-5-epi-valiolone 7-phosphate |
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For diagram of valiolone biosynthesis, click here |
| Glossary: |
2-epi-5-epi-valiolone = (2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-5-(hydroxymethyl)cyclohexan-1-one |
| Other name(s): |
AcbM |
| Systematic name: |
ATP:2-epi-5-epi-valiolone 7-phosphotransferase |
| Comments: |
The enzyme, characterized from the bacterium Actinoplanes sp. SE50/110, is involved in the biosynthesis of the oligosaccharide acarbose. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Zhang, C.S., Stratmann, A., Block, O., Bruckner, R., Podeschwa, M., Altenbach, H.J., Wehmeier, U.F. and Piepersberg, W. Biosynthesis of the C7-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway. J. Biol. Chem. 277 (2002) 22853–22862. [DOI] [PMID: 11937512] |
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| [EC 2.7.1.188 created 2015] |
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