| EC |
2.7.1.222 |
| Accepted name: |
4-hydroxytryptamine kinase |
| Reaction: |
ATP + 4-hydroxytryptamine = ADP + 4-hydroxytryptamine 4-phosphate |
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For diagram of psilocybin biosynthesis, click here |
| Glossary: |
psilocybin = 3-[2-(dimethylamino)ethyl]-1H-indol-4-yl phosphate |
| Other name(s): |
PsiK |
| Systematic name: |
ATP:4-hydroxytryptamine 4-phosphotransferase |
| Comments: |
Also acts on 4-hydroxy-L-tryptophan in vitro. Isolated from the fungus Psilocybe cubensis. Involved in the biosynthesis of the psychoactive compound psilocybin. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Fricke, J., Blei, F. and Hoffmeister, D. Enzymatic synthesis of psilocybin. Angew. Chem. Int. Ed. Engl. 56 (2017) 12352–12355. [DOI] [PMID: 28763571] |
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| [EC 2.7.1.222 created 2017] |
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