| EC |
2.7.1.3 |
| Accepted name: |
ketohexokinase |
| Reaction: |
ATP + D-fructose = ADP + D-fructose 1-phosphate |
| Other name(s): |
ketohexokinase (phosphorylating) |
| Systematic name: |
ATP:D-fructose 1-phosphotransferase |
| Comments: |
D-Sorbose, D-tagatose and 5-dehydro-D-fructose and a number of other ketoses and their analogues can also act as substrates [4]. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9030-50-6 |
| References: |
| 1. |
Cori, G.T., Ochoa, S., Slein, M.W. and Cori, C.F. The metabolism of fructose in liver. Isolation of fructose-1-phosphate and inorganic pyrophosphate. Biochim. Biophys. Acta 7 (1951) 304–317. [PMID: 14858418] |
| 2. |
Hers, H.G. La fructokinase du foie. Biochim. Biophys. Acta 8 (1952) 416–423. [PMID: 13208667] |
| 3. |
Parks, R.E., Ben-Gershom, E. and Lardy, H.A. Liver fructokinase. J. Biol. Chem. 227 (1957) 231–242. [PMID: 13449068] |
| 4. |
Raushel, F.M. and Cleland, W.W. Bovine liver fructokinase: purification and kinetic properties. Biochemistry 16 (1977) 2169–2175. [PMID: 193556] |
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| [EC 2.7.1.3 created 1961] |
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