The Enzyme Database

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Accepted name: streptomycin 6-kinase
Reaction: ATP + streptomycin = ADP + streptomycin 6-phosphate
Other name(s): streptidine kinase; SM 6-kinase; streptomycin 6-kinase (phosphorylating); streptidine kinase (phosphorylating); streptomycin 6-O-phosphotransferase; streptomycin 6-phosphotransferase
Systematic name: ATP:streptomycin 6-phosphotransferase
Comments: dATP can replace ATP; and dihydrostreptomycin, streptidine and
2-deoxystreptidine can act as acceptors.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37278-11-8
1.  Walker, J.B. and Skorvaga, M. Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives. J. Biol. Chem. 248 (1973) 2435–2440. [PMID: 4121456]
2.  Walker, J.B. and Walker, M.S. Streptomycin biosynthesis. Enzymatic synthesis of O-phosphorylstreptidine from streptidine and adenosinetriphosphate. Biochim. Biophys. Acta 148 (1967) 335–341. [DOI] [PMID: 6075410]
[EC created 1972, modified 1976]

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